Gather all ingredients.

Preheat oven to 400° F (200° C). Grease a 10x15x1-inch baking pan; set aside.

Cook and stir ground beef in a large skillet over medium heat until browned, 5 to 7 minutes. Drain off and discard grease.

Add pepper and onion to skillet. Cook over medium heat, stirring occasionally until vegetables are tender, about 5 minutes. Remove from heat.

Stir in ham, mushrooms, and pizza sauce. Set aside.

Unroll pizza crust onto prepared baking pan. Pat dough to a 9 x 13-inch rectangle.

Lay half of the pepperoni lengthwise over half of the crust to within 1/2-inch of the edge. Spoon meat mixture over the pepperoni.

Top with cheese and remaining pepperoni.

Fold dough over filling. Pinch ends and sides together with your fingers to seal the filling.

Poke holes in the top with the tip of a sharp knife. Brush with melted butter.

Bake in a preheated oven for 20 minutes or until golden brown.