Whisk together olive oil, wine, 2 tablespoons lemon juice, lemon zest, half of the garlic, crushed red pepper, oregano, 1 teaspoon salt, and 1/2 teaspoon pepper in a bowl. Add chicken and toss to coat. Cover and refrigerate for 30 minutes to 1 hour.

Stir together remaining salt and pepper with breadcrumbs, panko, Parmesan cheese, and garlic powder in a shallow dish. Remove chicken from marinade and coat in breadcrumb mixture, pressing to adhere. Thread chicken onto skewers and coat with olive oil cooking spray.

Preheat air fryer to 390°F (198°C). Air fry chicken skewers until crispy, golden brown, and cooked to an internal temperature of 165°F (74°C), approximately 12 minutes.